Features of Food Intolerance in Patients with Irritable Bowel Syndrome

The aim was to evaluate the activity of intestinal carbohydrases in patients with irritable bowel syndrome (IBS) symptoms food intolerance. Material and methods. 126 IBS (83 women 43 men, median age – 32.0 years (Q1–Q3: 27–38 years)) were examined. diagnosis established on basis Roman Criteria IV. A questionnaire conducted for all identify intolerances, according results which divided into three groups: first isolated intolerance foods a high content FODMAP; second milk dairy products; third combined To determine carbohydrates: lactase, sucrose, maltase glucoamylase, underwent esophagogastroduodenoscopy biopsy samples from duodenum. determined by Dahlquist method modification N.I. Belostotsky. control group consisted 30 conditionally healthy people (10 men 20 women, 33.9 24–35)), comparable gender IBS. enzymes this within reference values. Statistical data processing carried out using computer program Statistica 8.0. Results. According survey, it found that IBS, 52 (41.3%) believed they had certain foods. Isolated FODMAP noted 13 (10.3%) patients, 16 (12.7%) products, 23 (18.3%) indicated In FODMAP, glucoamylase 120.0 (68.5–209.2) ng/mg glucose per 1 mg tissue minute (ng/mg × min), 630.5 (480.7–951.0) min, sucrose 50.0 (32.8–68.8) lactase 10.5 (5.5–40.5) min. Comparing revealed statistically significant difference (p < 0.05) each enzyme studied.In studied also lower than group: 107.0 (64.0–174.0) 622.0 (481.5–887.0) 48.0 (35.5-60.0) 8.0 (3.0–22.5) Among presence (with products), significantly differed 0.05). 107.5 (57.5–194.2) 627.0 (480.7–911.7) - 47.5(34.8–61.5) 9.0 (4.0–28.8) Conclusion. Food who intolerances (isolated or as well products FODMAP), decrease (glucoamylase, maltase) compared 0.05), may indicate have disaccharidase deficiency